ISDIN stands for quality and trust. With over 40 years of experience and a commitment to research, the brand has become a leader in pharmaceutical skincare products. Under various names, ISDIN markets its products with a consistent philosophy: maximum efficacy and safety. From sun protection to treatments for atopic skin and anti-mosquito solutions, ISDIN offers a wide range of products to address your everyday needs.
This night facial cream is formulated with Melatonin to boost antioxidant defences, Carnosine to delay Advanced Glycation End-products (A.G.E.) formation, protecting collagen and elastin. Helichrysum Italicum stimulates calming molecules, enhancing well-being.
Pues mira, la verdad es que antes usaba un sérum de otra marca más conocida, pero no sé, no terminaba de convencerme... este de Isdin me está gustando mucho más, a ver si sigo notando los resultados.
Bonnie Blue | 02/10/2025
We had a misunderstanding, which was resolved quickly and professionally. Without a doubt, I will keep using Pharmacy Club. 100% reliable! Thanks a lot ^_^
Julia | 26/05/2026 13:18:01
Excellent service
Jo | 25/05/2026 14:08:21
I didn't need to contact the customer service team.
Janet | 20/05/2026 16:20:55
Excelente servicio.
Catalina | 19/05/2026 19:26:27
all goods
mair | 05/05/2026 16:59:37
Good
Tessy | 05/05/2026 11:10:24
Quick delivery got it within a week and had updates.
Komal | 03/05/2026 10:28:44
Never required customer service, however we are fully kept up to date with process, from purchase to delivery
Victoria | 30/04/2026 17:54:48
I bought theses because purchased them in Spain when had terrible ear pain on plane. Much better than others as they have different sizes & I need small.
Carole | 27/04/2026 16:09:20
Product as expected. Well wrapped and quickly despatched. Price was competitive as well
Marlyn | 22/04/2026 23:44:33
Good communication. Took a little while coming from outside the UK.
Jayne | 22/04/2026 07:46:50
Good website, easy to order used this company a few times now.
Jo | 19/04/2026 10:39:19
Royal Mail : Really nice folks
Martyn | 20/01/2026 09:49:51
Royal Mail : Took longer than advertised but not too bad considering coming from Spain
Susanne | 19/01/2026 19:05:18
Royal Mail : Delivery right on time and a very friendly happy delivery man.
Lillah | 19/01/2026 13:21:21
Royal Mail : Great delivery
Nick | 19/01/2026 11:18:28
Royal Mail : Took a few days longer than originally indicated. However, given the New Year holiday and severe snow here in north Scotland, a few days delay was very understandable.
Elma | 19/01/2026 09:49:50
Royal Mail : I’ve used Royal Mail multiple times and have always been satisfied. Delivery is reliable and usually fast, parcels arrive on time, and tracking lets you follow them at every stage. The postal staff are polite, and the system is convenient and easy to use. It’s reassuring to use their services, knowing your parcel is in good hands.
Elena | 19/01/2026 07:14:39
Royal Mail : Package arrived uneventfully.
Fiona | 15/01/2026 14:36:24
Royal Mail : On time, facil y rapido
Angelica Palazzo | 14/01/2026 13:06:19
Royal Mail : The delivery service was very efficient. Everything arrived in perfect condition and on the scheduled date.
Marina | 12/01/2026 11:45:37
Royal Mail : Never any issues. A great British institution that deserves support
Keith Channing | 11/01/2026 12:22:41
Royal Mail : Good delivery service, always making sure that they deliver the package to someone in the house or they leave it in a safe place.
Silvia | 10/01/2026 00:21:25
Royal Mail : quick delivery
Ahmad | 08/01/2026 07:16:17
| Calle Mesones, 6 | |
| 18001 Granada | |
| Online orders : +34 858952394 |
Pharmacist
Use our online service to make your enquiries in a comfortable and simple way.
Description
ISDIN
REVIEWS
How to use
Ingredients
Revitalize your skin with Retinal Smooth, a biphase facial night serum formulated with retinaldehyde and matrikines that gently accelerates skin renewal, helping to prevent early signs of aging and promoting a more radiant complexion. Perfect for those starting to use retinal for anti-aging benefits.
Benefits:
Brightens: With retinaldehyde and matrikines, it boosts skin radiance by +40% in 4 weeks. Repairs: Melatonin provides antioxidant action, helping to repair damage caused by free radicals. Soothes: Niacinamide alleviates redness and softens the skin, providing a comforting sensation. Hydrates: Enhances hydration, keeping skin nourished. Directions for Use:
Apply Retinal Smooth during your nighttime routine. If you experience discomfort, follow a retinization period: in the first week, apply three nights per week with 2-night intervals; in the second week, use every other night; from the third week onwards, if no irritation occurs, increase usage frequency.
Key Ingredients:
Retinaldehyde: Known for its renewing effect, it reduces early fine lines. Matrikines: Peptides that promote microcirculation and skin renewal. Melatonin: Repairs oxidative damage overnight. Niacinamide: Soothes redness and improves hydration.
Shop Online Isdinceutics Retinal Smooth Serum 50 ml at best price.
Product features:
- Treatments: Anti-wrinkle and Anti-aging
- Cosmetic Type: High End
- Textures: Serum
- Best Sellers: Retinol
- Skin Type: All Skin Types
Product Reference: #371388
Directions for Use:1. Cleanse your face thoroughly in the evening before applying the serum. 2. Shake the bottle well to mix the two phases. 3. Dispense a small amount of serum onto your fingertips. 4. Gently apply the serum to your face and neck, avoiding the eye contour area. 5. Allow the serum to absorb fully before applying any other skincare products. 6. If you are new to retinoids or have sensitive skin, start with a retinization period: Week 1: Apply three nights a week with 2-night intervals. Week 2: Apply every other night. Week 3 onwards: If no irritation occurs, apply nightly.
Recommended Frequency: Apply Isdinceutics Retinal Smooth Serum every night after cleansing for optimal results. If irritation occurs, reduce the frequency as described in the retinization period above.
Additional Tips:1. Always perform a patch test before the first application, especially if you have sensitive skin. 2. Sun Sensitivity: Retinaldehyde can increase sun sensitivity. Always use a broad-spectrum sunscreen with an SPF of 30 or higher during the day while using this product and for a week after discontinuing use.
3. Avoid Eye Area: Do not apply the serum to the eye contour area.
4. Consult a Dermatologist: If you experience persistent irritation or have any concerns, consult a dermatologist.
5. Storage: Store the product in a cool, dry place away from direct sunlight.
6. Combination with other products: Avoid using other exfoliating products simultaneously with this serum to prevent irritation.
7. Introduce Gradually: If you are using other active ingredients in your skincare routine, introduce this serum gradually to avoid potential interactions.